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IIT-D is developing catalytic technology for the long-term production of chiral APIs.

India is heavily reliant on imports for Active Pharmaceutical Ingredients (APIs), with chiral molecules accounting for a sizable proportion of those APIs. Chiral molecules are essential building blocks for the production of pharmaceuticals, agrochemicals, and biologically active compounds.

The Indian Institute of Technology Delhi (IIT-D) has developed a catalytic technology for the sustainable and cost-effective synthesis of chiral molecules. This research was funded by the Science and Engineering Research Board (SERB), a statutory body of the Government of India’s Department of Science and Technology (DST).

The research team created a Metal-Organic Frameworks (MOFs)-based catalytic technology that uses inexpensive natural feedstocks and abundant metals to create enantiomerically pure chiral molecules in a sustainable and cost-effective manner.

“The developed catalytic technology may play a critical role in decreasing the country’s reliance on the import of Active Pharmaceutical Ingredients, which also means lower input costs for the industry, encouraging it to pass on the benefit to society,” said Prof. Kuntal Manna, Chemistry Dept., IIT Delhi.

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